Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than others.

The Seattle Seahawks' primary rivals, the San Francisco 49ers, might be the only other team in the league that can rival the injury concerns Seattle has dealt with this season. During Week 7, the 49ers lost 28-18 to the Kansas City Chiefs in their Super Bowl

Latest injury update on Brandon Aiyuk, who injured his leg and was carted off during the 49ers' game against the Chiefs on Sunday.

It’s certainly been a rough start to a pivotal season for the San Francisco 49ers, but one anonymous NFL executive thinks the team should go to extremes to fix it. In his weekly day-after-games column,

The Kansas City Chiefs earned an impressive victory over the formidable San Fransisco 49ers on Sunday, and are riding high heading into their Week 8 matchup against the

The Kansas City Chiefs beat the San Francisco 49ers 28-18 to improve to 6-0 on the season. Meanwhile, the San Francisco 49ers fall to 3-4 behind Brock Purdy’s 3 INTs. Nick Wright, Chris Broussard, and Kevin Wildes ask if Purdy is to blame for the

Fresh off their bye week, the Dallas Cowboys will try to win their fourth straight road game to start the season when they play the San Francisco 49ers.

The San Francisco 49ers rookie was shot through the chest during an armed robbery attempt in late August Against all odds, Ricky Pearsall was back where he was always supposed to be this weekend: on the football field.

Pearsall (chest) remains listed as questionable but is on track to make his NFL debut in Sunday's game against the Chiefs, Jay Glazer on Fox Sports reports. Pearsall (chest) was activated off the reserve/non-football injury list Saturday after he turned in a trio of full practices during Week 7 prep.