One, the agouti-related protein (AGRP) and neuropeptide Y (NPY) neurons, stimulates hunger, while the other, pro-opiomelanocortin (POMC) neurons, curbs it. This delicate balance orchestrates ...

The best characterized pathways are the orexigenic neuropeptide Y/Agouti-related protein and the anorexigenic pro-opiomelanocortin/cocaine- and amphetamine-related transcript neurons in the ...

Agouti-related peptide is an endogenous antagonist of the MC4R that works with neuropeptide Y to stimulate appetite, whereas MC4R agonists such as α- and β-melanocyte-stimulating hormone promote ...

Agouti-related peptide is an endogenous antagonist of the MC4R that works with neuropeptide Y to stimulate appetite, whereas MC4R agonists such as α- and β-melanocyte-stimulating hormone promote ...

4,5 These ghrelin-containing neurons send efferent fibers to neurons that contain neuropeptide Y (NPY) and agouti-related protein (AgRP)—NPY/AgRP neurons—and might stimulate the release of ...