Medscape5d
Molluscum Contagiosum Virus
Future Virology. 2013;8(6):561-573. Apoptosis is an effective mechanism to destroy virus-infected cells. Central to this process is the interaction of FADD and procaspase-8. [58] During TNFR-1 ...
Nature5d
Ubiquitin-binding domains — from structures to functions
Ubiquitin is an intracellular signalling molecule that is conjugated to various proteins. Ubiquitin conjugation to itself yields Lys- or Met-conjugated chains, thus expanding its repertoire of ...
Frontiers5d
The Two NF-κB Pathways Regulating Bacterial and WSSV Infection of Shrimp
Bacterial infection can be recognized by Toll and IMD pathways, which activate two NF-κB transcription factors, Dorsal and Relish, respectively, to eventually lead to boosting the expression of ...
Frontiers5d
The Therapeutic Potential of Targeting NIK in B Cell Malignancies
In response to certain signals and ligands, such as CD40, BAFF and lymphotoxin-β activation, NIK protein stabilization and subsequent NF-κB activation is achieved. Overexpression or overactivation of ...