Writer and creator Jonathan Larson died in the early morning hours of Jan. 25, the same day of the New York Theater Workshop premiere. Larson was 35 and died from sudden aortic dissection as a result ...

The event was hosted by Local 10 News Anchor Kristi Krueger. About one in every 5,000 people have Marfan syndrome, a genetic disorder that affects the connective tissues that hold organs in place.

At 27, she lives with Marfan syndrome, a genetic disorder that affects the connective tissues that hold organs in place. An eye appointment as a teenager led to the diagnosis. “I thought I had ...

The Jonathan Larson Project is now in rehearsal in preparation for its world premiere run at the Orpheum Theatre off-Broadway for 16 weeks only, beginning Friday, February 14 with an official ...

Andy Mientus added: "The fact that I am here, premiering Jonathan Larson work... I thought that was it, I thought 'Rent, Tick, Tick... BOOM!, we have it all,' we do not have it all. There is a ...

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Despite high penetrance, one of the unexplained features of MFS and related fibrillinopathies is the prominent phenotype variation in the timing of onset, tissue distribution, and severity of ...

Background Resveratrol, a dietary supplement that intervenes in cellular metabolism, has been shown to reduce aortic growth rate in a mouse model of Marfan syndrome (MFS), a condition associated in ...

2 Centre National de Référence pour le syndrome de Marfan et apparentés, Hôpital Bichat, AP-HP, Paris, France Background Bicuspid aortic valve (BAV) is related to aortic dilatation, but patterns/rates ...

In light of the effects that PP2A can exert on the mTOR pathway, we hypothesized that PP2A activation by small-molecule activators of PP2A could mitigate AA progression in Marfan syndrome (MFS). Two ...

Department of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan. (H. Yagi, H.A., Q.L., A.S.-K., M.U., H.K., R.M., A.S., S.O., H.T., Norifumi Takeda ...