Nature6d
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
Unlike the role of RIP in recruitment of the IκB kinase (IKK)-complex to the TNFR, which leads to the activation of NF-κB, the kinase activity of RIP has death-promoting activity that is ...
Nature6d
Kinases articles from across Nature Portfolio
Kinases are enzymes that catalyze the addition of a phosphate group (PO43−) to substrates, usually proteins. The phosphate generally comes from adenosine triphosphate (ATP). Kinases and ...