Ayton was helped back to the locker room after sustaining an apparent calf injury in the third quarter of Monday's game against the Nuggets, Danny Marang of 1080 The Fan Portland reports. Ayton's injury looked to be of the non-contact variety,

Portland Trail Blazers center Deandre Ayton and point guard Scoot Henderson have been ruled out for Wednesday night’s game at the Denver Nuggets. Ayton (left calf strain) left Monday night’s 146-117 loss at Denver in the third quarter and did not return.

In Monday night’s game between the Blazers and Nuggets, Portland center Deandre Ayton suffered a non-contact injury to his leg. In the third quarter, Ayton grabbed his leg and immediately reacted under the basket after an offensive possession.