The Lancet21d
TACE plus immune checkpoint inhibitor-based systemic therapies for hepatocellular carcinoma
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C&EN29d
Discovery of Novel Small-Molecule Inhibitors Disrupting the MTDH-SND1 Protein–Protein Interaction
State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China Department of Medicinal Chemistry, School ...
Frontiers1mon
Potential role of gut-related factors in the pathology of cartilage in osteoarthritis
Another study further investigated the possible mechanism and found that INT 777 inhibited the phosphorylation of p38 and the activation of the IκB kinase (IKK)/inhibitor of nuclear factor kappa B ...
C&EN1mon
Novel PD-L1/VISTA Dual Inhibitor as Potential Immunotherapy Agents
State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China Department of Medicinal Chemistry, School ...
Business Wire1mon
DeepCure Unveils STAT6 Inhibitor Program with Novel Oral Small Molecules Targeting Type 2 Inflammation
These next-generation STAT6 inhibitors demonstrate excellent oral bioavailability, cell permeability, and metabolic stability, and do not target STAT6 for degradation. DeepCure expects to select a ...