Selenium works by inhibiting a protein found in the cytoplasm called Nuclear-factor kappa-B (NF-kB). When NF-kB is released from its inhibitor I-kB, it increases both inflammation and viral ...

A research team led by Prof. WENG Jianping from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) revealed that insulin-like growth factor-binding ...

and exerts its anti-inflammatory effects via the major vault protein (MVP)-c-Jun N-terminal kinase (JNK)/nuclear factor kappa B (NF-κB) signaling axis. In animal models, systemic and endothelial ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...