Frontiers17d
5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation
pcDNA3.1-IKKβ plasmid was purchased from Genscript Co., Ltd. (Nanjing, China). Antibodies against p-IκBα, IκBα, p-p65, and p65 were purchased from Bioworld Technology, Inc. (Nanjing, China); Antibody ...
Frontiers25d
The beneficial effects of curcumin on aging and age-related diseases: from oxidative stress to antioxidant mechanisms, brain health and apoptosis
ROS and reactive nitrogen species (RNS) are produced in our cells which have either an endogenous origin such as metabolic pathways (e. g. the tricarboxylic acid (TCA) cycle, the respiratory chain, ...
eLife27d
Chromatin activity of IκBα mediates the exit from naïve pluripotency
This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...