The 49ers have given Deebo Samuel permission to seek a trade. George Kittle believes San Francisco will have trouble replacing him.

The 49ers have given wide receiver Deebo Samuel permission to talk to teams that might be interested in trading for him this offseason and that is likely the first step toward Samuel's departure after six seasons with the team.

While Deebo Samuel’s future with the 49ers remains uncertain, Kittle's remarks highlight both the challenge of moving forward without him and the optimism surrounding the team’s offensive weapons heading into the 2025 season.

Deebo Samuel requested to leave the San Francisco 49ers, and his teammate, George Kittle, knows it will be a significant loss for the upcoming season. The upcoming season for the San Francisco 49ers will definitely not be like the previous ones.